news
Home > news > Company news about In 1991, chitosan was hailed by European and American academic circles as the sixth element of life after protein, fat, sugar, vitamins and inorganic salts.
Events
Contact Us
86-0532-85171476
Contact Now

In 1991, chitosan was hailed by European and American academic circles as the sixth element of life after protein, fat, sugar, vitamins and inorganic salts.

2024-07-22

Latest company news about In 1991, chitosan was hailed by European and American academic circles as the sixth element of life after protein, fat, sugar, vitamins and inorganic salts.
  "Chitosan" (chitin) is an animal polymer cellulose extracted from crab and shrimp shells through genetic engineering. It is the only one discovered in the world. It also has: cationic properties, alkaline, polysaccharide Natural substances from human body and animal fibers. In 1991, it was praised by the global medical community as "the sixth life element of the human body". Therefore, it has been recognized as a functional health food by the European, American, Chinese and Japanese governments. Plants such as Ganoderma lucidum and Cordyceps sinensis also contain trace amounts of "chitosan", but the content is only between 2% and 7%. "Chitosan" (chitin) is the only positively charged positive animal fiber known to humans.
The substance "chitosan" is an animal cellulose derivative. Take a look at the structure of plant cellulose. The structure of D-glucose has changed on the second carbon chain (draw a structural diagram of D-type six-carbon sugar). Usually, plant cellulose has a hydroxyl group hanging on the second carbon element. Then chitin animal cellulose is linked to acetyl glucosamine. This kind of animal cellulose was discovered by the Frenchman Ogier in the early 19th century. It is quite stable, insoluble in water, soluble in strong acids, and soluble in alkali, and has great effects on humans.
  In 1991, chitosan was praised by the European and American academic community as the sixth life element after protein, fat, sugar, vitamins and inorganic salts. It is completely different from general nutritional supplements and has five major functions for the human body: immune enhancement, inhibiting aging, preventing diseases, promoting disease recovery and regulating the physiological functions of the human body. The physiological effects on the human body are mainly achieved through the action of chitosan. According to literature reports, the disease prevention and health care effects are briefly described as follows:
Strengthening immune function and inhibiting cancer
Chitosan has the functions of regulating and improving the body's immunity, promoting antibody production and enhancing the body's disease resistance. The degradation product of chitin, glucosamine, changes the pH value of body fluids, activates lymphocytes and inhibits the metastasis of cancer cells [3].
Professor Shigehiro Hirano of Tottori University in Japan transplanted cancer cells into rats to cause skin cancer. The rats were divided into two groups. One group of rats was given "chitosan" and the cancer cells disappeared. The other group of rats that were not given "chitosan" all died. In the rabbit experiment, the cancer cells were also restored to normal cells after being given "chitosan". As an auxiliary treatment in the clinic, "chitosan" has a good effect on early cancer. For mid- and late-stage cancer, combined with specialized treatment, it can improve the efficacy, reduce pain, and prolong life. Its anti-cancer mechanism is:
1. Inhibit cancer cell toxins
When you have cancer, you will lose weight rapidly, become emaciated, anemic, and have a loss of appetite. This is because cancer cells release cancer toxins, which reduce the iron in the serum and cause anemia; they act on the satiety center to lose appetite, accelerate fat decomposition and protein decomposition in the body, and cause weight loss, or even cachexia. Cancer patients develop appetite after taking chitosan because it has an inhibitory effect on cancer cell toxins.
2. Activate lymphocytes that can kill cancer cells
There are a large number of lymphocytes in the body (such as NK cells and LAK cells), which can decompose normal cells and cancer cells. This is the immune function of the human body. The role of lymphocytes in killing cancer cells is most active at around pH 7.4. The metabolic characteristics of cancer cells are mainly anaerobic glycolysis of sugars, and lactic acid is generated during metabolism. Therefore, lymphocytes that have the ability to kill tumors are inhibited in the acidic environment around cancer cells. Chitosan shifts the pH of body fluids to the alkaline side of 0.5, creating an environment for lymphocytes to attack cancer cells.
3. Inhibit cancer cell metastasis
Cancer cells generally metastasize through blood vessels. There is a bonding factor on the surface of vascular endothelial cells. Cancer cells can enter blood vessels only after they attach and bind to the bonding factor, then move by binding to the bonding factor in the blood, and then bind to bonding factors in other parts and adhere to form cancer thrombi to become metastatic foci. Chitosan has a strong adsorption effect on the bonding factor. Cancer cells cannot metastasize if they cannot find a substance to bind to.
Lower cholesterol
  Cholesterol is an indispensable substance in the body. In addition to being a component of cell membranes, it can be converted into bile acids, steroid hormones and vitamin D in the body. Normal cholesterol metabolism is beneficial to the body. However, excessive cholesterol accumulates on the blood vessel wall, narrows the blood vessel cavity, and obstructs blood flow. Myocardial ischemia and hypoxia cause angina pectoris. High cholesterol blood viscosity is prone to thrombosis, partial myocardial necrosis, and myocardial infarction. Cerebral thrombosis can cause cerebral infarction.
Chitosan can lower cholesterol and its mechanism is:
1. Hindering the absorption of cholesterol in the body
After cholesterol in food enters the body, it needs to be transformed into cholesterol ester by enzymes before it can be absorbed in the intestines. This process requires the participation of bile acid. Bile acid is a surfactant that has an emulsifying effect on lipids. Chitosan easily combines with bile acid and is completely excreted from the body. Since the bile acid around cholesterol disappears, this enzyme cannot convert cholesterol into cholesterol ester that is easily absorbed by the intestine.
2. Hindering the absorption of fat
Because chitosan is a positively charged cationic compound, it gathers around negatively charged fat droplets in the body, forming a barrier that hinders absorption. At the same time, it can also combine with bile acid to affect lipid emulsification and reduce its absorption.
3. Promoting cholesterol conversion
Cholesterol is converted into bile acid in the liver. Bile acid is an important component of digestive juice and has a certain amount of reserves in the gallbladder. Bile acid is usually reabsorbed by the small intestine and returned to the liver after completing the digestion and absorption of fat. This is the "enterohepatic circulation" of bile acid. Because chitosan easily combines with bile acid and is completely excreted from the body. Then, in order to maintain the normal content of bile acid, cholesterol must be converted into bile acid in the liver, and as a result, the cholesterol content in the blood will inevitably decrease.
Hypotensive effect
The principle of treatment for primary hypertension is to limit salt intake, and about 60% of patients can lower their blood pressure. Experiments have shown that increased blood pressure is only related to chloride ions in salt, but not sodium ions. Chloride ions in salt can activate angiotensin converting enzyme, which catalyzes angiotensin I (decapeptide) to angiotensin II (octapeptide). Angiotensin II promotes aldosterone secretion to retain sodium and water in the body, increase blood volume and increase blood pressure. Chitosan is positively charged and attracts chloride ions, and is excreted in the feces. The body lacks chloride ions, the converting enzyme is inactive, angiotensin II is reduced, and blood pressure no longer rises.
Hypoglycemic effect
Due to insulin deficiency (absolute or relative), diabetes is caused by acidic body fluids (sugar metabolism disorder, lipid metabolism disorder, incomplete fat oxidation, ketone body). If the pH drops by 0.1, insulin sensitivity drops by 30%, the patient's sugar utilization decreases, and hyperglycemia occurs. Chitosan adjusts the pH to a weak alkaline state, improves insulin utilization, and is beneficial to the prevention and treatment of diabetes. In addition, it also has the function of regulating the endocrine system, normalizing insulin secretion, and inhibiting blood sugar rise. Most adult diabetes is related to obesity, which reduces receptor sensitivity or the number of receptors. Chitosan can eliminate excess sugar, prevent obesity, and is beneficial to the prevention and treatment of diabetes.
Strengthening liver function
The liver is the largest gland in the human body and has a variety of metabolic functions. It plays an important role in the metabolism of proteins, sugars, lipids, vitamins, hormones and other substances. At the same time, the liver also has functions such as secretion, excretion, and biotransformation. The functions of chitosan in strengthening liver function are listed as follows:
1. Lower cholesterol and fat, prevent fatty liver and hepatitis
According to the research of Professor Hirano of Tottori University in Japan, feeding rabbits with high cholesterol feed will cause fatty liver and hepatitis soon after due to the increase in the concentration of cholesterol and neutral fat in the blood, and the liver will be red. However, the liver of rabbits fed with chitosan at the same time will be normal dark brown.
2. Promote the production of hepatitis virus antibodies
There is no specific medicine for the treatment of viral hepatitis. The efficacy of high-dose interferon in the treatment of hepatitis B or hepatitis C is up to 50%. If chitosan is used in combination with interferon, the efficacy can be improved, the production of hepatitis virus antibodies can be promoted, and the hepatitis B virus can be turned negative.
3. Enhance the biotransformation function of the liver
Ethanol is converted into acetaldehyde under the action of liver alcohol dehydrogenase. Acetaldehyde is highly toxic and can cause headaches, nausea, liver damage, etc. Under normal circumstances, acetaldehyde is oxidized into acetic acid under the action of aldehyde dehydrogenase, and acetic acid is further oxidized into CO: and H. 0, eliminating toxicity. Chitosan can activate liver function, enhance the activity of aldehyde dehydrogenase, sober up and prevent alcoholic liver damage.
 

Send your inquiry directly to us

Privacy Policy China Good Quality Dried Mealworms Supplier. Copyright © 2023-2024 drymealworm.com . All Rights Reserved.